Kinetics of nitric oxide scavenging by ruthenium(III) polyaminocarboxylates: Novel therapeutic agents for septic shock

被引：87

作者：

Davies, NA

Wilson, MT

Slade, E

Fricker, SP

Murrer, BA

Powell, NA

Henderson, GR

机构：

[1] JOHNSON MATTHEY TECHNOL CTR, READING RG9 4NH, BERKS, ENGLAND

[2] UNIV ESSEX, SCH BIOL & CHEM SCI, COLCHESTER CO4 3SQ, ESSEX, ENGLAND

来源：

CHEMICAL COMMUNICATIONS | 1997年 / 01期

关键词：

D O I：

10.1039/a606463i

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The reaction of two representative ruthenium(III) polyaminocarboxylates with nitric oxide are rapid (k > 10(7) M(-1) S-1 at pH 7.4 and 7.3 degrees C) forming tight (K = 10(8) M(-1)) ruthenium(II) mononitrosyls.

引用

页码：47 / 48

页数：2

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