Phosphotyrosine-binding domains in signal transduction

被引：279

作者：

Yaffe, MB ^{[1
]}

机构：

[1] MIT, Ctr Canc Res, Dept Biol, Cambridge, MA 02139 USA

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2002年 / 3卷 / 03期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1038/nrm759

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Protein phosphorylation provides molecular control of complex physiological events within cells. In many cases, phosphorylation on specific amino acids directly controls the assembly of multiprotein complexes by recruiting phospho-specific binding modules. Here, the function, structure and cell biology of phosphotyrosine-binding domains is discussed.

引用

收藏

页码：177 / 186

页数：10

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