Nonracemic diarylmethanols from CuH-Catalyzed hydrosilylation of diaryl ketones

被引：64

作者：

Lee, Ching-Tien ^{[1
]}

Lipshutz, Bruce H. ^{[1
]}

机构：

[1] Univ Calif Santa Barbara, Dept Chem & Biochem, Santa Barbara, CA 93106 USA

来源：

ORGANIC LETTERS | 2008年 / 10卷 / 19期

关键词：

D O I：

10.1021/ol801590j

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient method for the synthesis of nonracemic diarylmethanols has been developed. The use of (R)-(-)-(DTBM-SEGPHOS)CuH effects highly enantioselective 1,2-hydrosilylation of prochiral diaryl ketones.

引用

页码：4187 / 4190

页数：4

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