Validation of a French Version of the 8-Item Morisky Medication Adherence Scale in Hypertensive Adults

被引:113
作者
Korb-Savoldelli, Virginie [1 ,2 ]
Gillaizeau, Florence [3 ,4 ]
Pouchot, Jacques [5 ]
Lenain, Emilie [3 ]
Postel-Vinay, Nicolas [6 ]
Plouin, Pierre-Francois [6 ]
Durieux, Pierre [3 ,4 ]
Sabatier, Brigitte [1 ,7 ]
机构
[1] Hop Europe Georges Pompidou, Assistance Publ Hop Paris, Serv Pharm, F-75015 Paris, France
[2] Univ Paris 05, Fac Pharm, Lab Pharm Clin & Pharmacocine, Paris, France
[3] Hop Europe Georges Pompidou, Assistance Publ Hop Paris, Unite Epidemiol & Rech Clin, F-75015 Paris, France
[4] INSERM, Ctr Invest Epidemiol, Paris, France
[5] Hop Europe Georges Pompidou, Assistance Publ Hop Paris, Serv Med Interne, F-75015 Paris, France
[6] Hop Europe Georges Pompidou, Assistance Publ Hop Paris, Serv Hypertens, F-75015 Paris, France
[7] Univ Paris 05, INSERM, U765, Paris, France
关键词
D O I
10.1111/j.1751-7176.2012.00634.x
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
J Clin Hypertens (Greenwich). 2012; 14:429434. (c) 2012 Wiley Periodicals, Inc. The aim of this study was to validate a French translation of the structured self-report 8-item Morisky Medication Adherence Scale (MMAS-8) and determine its psychometric properties in patients taking antihypertensive medication. An observational cross-sectional study was conducted in the hypertensive unit of a French university hospital. The MMAS-8 was translated according to international guidelines. Internal consistency was assessed using Cronbach a coefficient, construct validity using principal component and confirmatory factor analyses, and the test-retest reliability at 1-month interval using the intraclass correlation coefficient (ICC). Three levels of adherence were considered (low: scores of 0 to <6; medium: 6 to <8; high: 8) and risk factors were explored in ordinal logistic regression models. A total of 199 patients were included: mean age, 55.7 +/- 14.6 years, 57.3% men (114 of 199), and 39.5% (66 of 167) had uncontrolled blood pressure. The French MMAS was moderately reliable (a=0.54), one-dimensional, and reproducible (ICC=0.68). The mean score was 6.96 (standard deviation 1.25) and 17.6% (35 of 199), 37.7% (75 of 199), and 43.7% (87 of 199) of patients had low, medium, and high adherence, respectively. The only factor significantly associated with adherence was age. The French MMAS has acceptable psychometric effects to measure medication adherence in hypertensive patients and may be useful in detecting nonadherent hypertensive patients.
引用
收藏
页码:429 / 434
页数:6
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