Surface-enhanced Raman detection on metalized nanostructured poly(p-xylylene) films

被引:74
作者
Kao, Ping [2 ,3 ]
Malvadkar, Niranjan A. [1 ]
Cetinkaya, Murat [1 ]
Wang, Hui [1 ]
Allara, David L. [2 ,3 ]
Demirel, Melik C. [1 ]
机构
[1] Penn State Univ, Dept Engn Sci, University Pk, PA 16802 USA
[2] Penn State Univ, Dept Chem, University Pk, PA 16802 USA
[3] Penn State Univ, Dept Mat Sci & Engn, University Pk, PA 16802 USA
关键词
D O I
10.1002/adma.200800936
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The development of a SERS substrate with high uniformity and sample-to-sample reproducibility is reported. Nanostructured poly(p-xylylene) films are prepared using an oblique-angle polymerization method, and SERS-active metals are deposited onto the nanostructured polymer by using thermal evaporation (see figure). The use of the substrate for a robust and reagentless detection of both Gram-positive and Gram-negative bacteria is demonstrated.
引用
收藏
页码:3562 / +
页数:5
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