Growth, developmental milestones and health problems in the first 2 years in very preterm infants compared with term infants:: a population based study

被引:30
作者
Bucher, HU [1 ]
Killer, C [1 ]
Ochsner, Y [1 ]
Vaihinger, S [1 ]
Fauchère, JC [1 ]
机构
[1] Univ Zurich Hosp, Clin Neonatol, CH-8091 Zurich, Switzerland
关键词
growth development; health problems; very preterm infants;
D O I
10.1007/s00431-001-0898-0
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
The outcome of very preterm infants varies widely from centre to centre and from country to country. The aim of this study was to evaluate growth, developmental milestones and post-discharge morbidity of infants born before 32 weeks of gestation in Switzerland. A questionnaire was sent to the parents of 456 survivors born in 1996. A total of 309 (68%) parents responded and their infants were matched with 309 control infants born at term. At the corrected age of 24 months, the very preterm infants had significantly lower weight (-1.0 z-scores), lower length (-1.23 z-scores), and lower head circumference (-0.64 z-scores). Very preterm infants were reported to eat with a spoon later than those born at term (50% at 7.5 months corrected for prematurity versus 10 months, P<0.001), to drink later out of a cup (50% at 16.5 months versus 13.5 months, P=0.03) and to walk later independently (50% at 14.5 months versus 13.5 months, P=0.04), whereas timing of sitting unsupported was no different (50% at 7.4 months versus 7.2 months, P=0.9). Of very preterm infants, 16% were not able to walk at least three steps unsupported at 18 months after term which puts them at an increased risk for cerebral palsy. Some 35% of very preterm infants had to be readmitted to hospital during the first 24 months compared with 20% of control infants born at term (P<0.05). There was no difference between very preterm and term infants in respect to episodes of fever >38.5degreesC, episodes of coughing >3 days and treatment with antibiotics. Conclusion: these data based on a national survey allow to quantify growth retardation, developmental delay and post-discharge health problems within the first 2 years in preterm infants born before 32(0)/(7) weeks.
引用
收藏
页码:151 / 156
页数:6
相关论文
共 21 条
[11]  
LARGO RH, 1985, DEV MED CHILD NEUROL, V27, P183
[12]   Body proportionality in growth-retarded VLBW infants [J].
Largo, RH ;
vonSiebenthal, K ;
Etter, K ;
Morales, C ;
Bucher, HU ;
Duc, G .
JOURNAL OF PERINATAL MEDICINE, 1997, 25 (01) :17-25
[13]   Catch-up growth in 166 small-for-gestational age premature infants weighing less than 1,000 g at birth [J].
Monset-Couchard, M ;
de Bethmann, O .
BIOLOGY OF THE NEONATE, 2000, 78 (03) :161-167
[14]   THE SOMATIC GROWTH OF A REGIONAL BIRTH COHORT OF 351 PRETERM INFANTS DURING THE 1ST 2 YEARS OF LIFE [J].
PIEKKALA, P ;
KERO, P ;
SILLANPAA, M ;
ERKKOLA, R .
JOURNAL OF PERINATAL MEDICINE, 1989, 17 (01) :41-49
[15]   Reference data for head circumference-for-length in preterm low-birth-weight infants [J].
Roche, AF ;
Guo, SS ;
Wholihan, K ;
Casey, PH .
ARCHIVES OF PEDIATRICS & ADOLESCENT MEDICINE, 1997, 151 (01) :50-57
[16]  
Schubiger G, 1999, SCHWEIZ MED WSCHR, V129, P1025
[17]  
SONNANDER K, 1987, DEV MED CHILD NEUROL, V29, P351
[18]  
Stutchfield P, 2000, Clin Perform Qual Health Care, V8, P14, DOI 10.1108/14664100010332748
[19]   Intravenous nutrition and postnatal growth of the micropremie [J].
Thureen, PJ ;
Hay, WW .
CLINICS IN PERINATOLOGY, 2000, 27 (01) :197-+
[20]   Outcome of very preterm birth: children reviewed with ease at 2 years differ from those followed up with difficulty [J].
Tin, W ;
Fritz, S ;
Wariyar, U ;
Hey, E .
ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION, 1998, 79 (02) :F83-F87