Effects on apoptosis and reactive oxygen species formation by Jurkat cells exposed to 50 Hz electromagnetic fields

被引:35
作者
Palumbo, R
Capasso, D
Brescia, F
Mita, P
Sarti, M
Bersani, F
Scarfi, MR
机构
[1] CNR, Inst Electromagnet Sensing Environm, I-80124 Naples, Italy
[2] CNR, Inst Biostruct & Bioimaging, I-80125 Naples, Italy
[3] Univ Bologna, Dept Phys, Ist Nazl Biostrutture & Biosistemi, I-40126 Bologna, Italy
关键词
ELF fields; T-leukaemia cells; ROS formation; apoptosis;
D O I
10.1002/bem.20199
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The effect of exposure to 50 Hz electromagnetic field on a human T-leukaemia cell line (Jurkat) was investigated by evaluating the reactive oxygen species (ROS) production and apoptosis, both spontaneous and induced by a specific anti Fas/CD95 monoclonal antibody (anti-Fas). Our results suggest that 1 h intermittent (5 min field on/ 10 min field off) exposure does not affect ROS formation, while a slight but statistically significant decrease of both spontaneous and anti-Fas-induced apoptosis was observed.
引用
收藏
页码:159 / 162
页数:4
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