The contribution of magnetic resonance imaging to the diagnosis of multiple sclerosis

被引：220

作者：

Fazekas, F

Barkhof, F

Filippi, M

Grossman, RI

Li, DKB

McDonald, WI

McFarland, HF

Paty, DW

Simon, JH

Wolinsky, JS

Miller, DH

机构：

[1] Graz Univ, Dept Neurol, A-8036 Graz, Austria

[2] Graz Univ, MRI Ctr, A-8036 Graz, Austria

[3] Vrije Univ Hosp, Amsterdam, Netherlands

[4] Univ Milan, Dept Neurosci, Neuroimaging Res Unit, Sci Inst Osped San Raffaele, I-20122 Milan, Italy

[5] Univ Penn, Med Ctr, Philadelphia, PA 19104 USA

[6] Univ British Columbia, Vancouver, BC V5Z 1M9, Canada

[7] Inst Neurol, London WC1N 3BG, England

[8] NIH, Bethesda, MD 20892 USA

[9] Univ Colorado, Hlth Sci Ctr, Denver, CO USA

[10] Univ Texas, Sch Med, Houston, TX USA

来源：

NEUROLOGY | 1999年 / 53卷 / 03期

关键词：

D O I：

10.1212/WNL.53.3.448

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

MRI is very sensitive in showing MS lesions throughout the CNS, Using MRI for diagnostic purposes, however useful, is a complex issue because of limited specificity of findings and a variety of options as to when, how, and which patients to examine. Comparability of data and a common view regarding the impact of MRI are needed. Following a review of the typical appearance and pattern of MS lesions including differential diagnostic considerations, we suggest economic MRI examination protocols for the brain and spine. Recommendations for referral to MRI consider the need to avoid misdiagnosis and the probability of detecting findings of diagnostic relevance. We also suggest MRI classes of evidence for MS to determine the diagnostic weight of findings and their incorporation into the clinical evaluation. These proposals should help to optimize and standardize the use of MRI in the diagnosis of MS.

引用

页码：448 / 456

页数：9