1,2-vs 1,4-addition of acylbenzotriazoles to α,β-unsaturated aldehydes and ketones.: A novel route to 3-alkyl-4,6-diaryl-3,4-dihydropyran-2-ones

被引：23

作者：

Katritzky, AR ^{[1
]}

Denisko, OV ^{[1
]}

机构：

[1] Univ Florida, Dept Chem, Ctr Heterocycl Cpds, Gainesville, FL 32611 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2002年 / 67卷 / 09期

关键词：

D O I：

10.1021/jo011082s

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Lithiation of aliphatic 1-acylbenzotriazoles with subsequent reaction with alpha,beta-unsaturated ketones,13 and aldehydes affords either 3,4,6-trisubstituted 3,4-dihydropyran-2-ones or 1,3-dienes depending on the carbonyl reagent used. Substituent effects on product yield and isomer ratio are discussed.

引用

页码：3104 / 3108

页数：5