Does a new polyomavirus contribute to Merkel cell carcinoma?

被引:20
作者
Garneski, Kelly M. [1 ,2 ]
DeCaprio, James A. [3 ,4 ,5 ]
Nghiem, Paul [1 ,2 ,6 ]
机构
[1] Univ Washington, Dept Med, Seattle, WA 98109 USA
[2] Univ Washington, Dept Dermatol & Pathol, Seattle, WA 98109 USA
[3] Dana Farber Canc Inst, Dept Med Oncol, Boston, MA 02115 USA
[4] Brigham & Womens Hosp, Dept Med, Boston, MA 02115 USA
[5] Harvard Univ, Boston, MA 02115 USA
[6] Fred Hutchinson Canc Res Ctr, Div Clin Res, Seattle, WA 98109 USA
关键词
D O I
10.1186/gb-2008-9-6-228
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
A new technique designed to hunt for non-human transcripts has identified a novel SV40-like virus present in the majority of Merkel cell carcinomas. Here we examine what it will take to determine whether or not this virus contributes to carcinogenesis.
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页数:4
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共 23 条
[1]   BK virus infection, replication, and diseases in pediatric kidney transplantation [J].
Acott, Philip D. ;
Hirsch, Hans H. .
PEDIATRIC NEPHROLOGY, 2007, 22 (09) :1243-1250
[2]   Epidemiology of primary Merkel cell carcinoma in the United States [J].
Agelli, M ;
Clegg, LX .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2003, 49 (05) :832-841
[3]   Cellular transformation by SV40 large T antigen: interaction with host proteins [J].
Ali, SH ;
DeCaprio, JA .
SEMINARS IN CANCER BIOLOGY, 2001, 11 (01) :15-22
[4]   Identification of a third human polyomavirus [J].
Allander, Tobias ;
Andreasson, Kalle ;
Gupta, Shawon ;
Bjerkner, Annelie ;
Bogdanovic, Gordana ;
Persson, Mats A. A. ;
Dalianis, Tina ;
Ramqvist, Torbjorn ;
Andersson, Bjorn .
JOURNAL OF VIROLOGY, 2007, 81 (08) :4130-4136
[5]   Sustained remission of metastatic Merkel cell carcinoma with treatment of HIV infection [J].
Burack, J ;
Altschuler, EL .
JOURNAL OF THE ROYAL SOCIETY OF MEDICINE, 2003, 96 (05) :238-239
[6]   Role of the interaction between large T antigen and Rb family members in the oncogenicity of JC virus [J].
Caracciolo, V. ;
Reiss, K. ;
Khalili, K. ;
De Falco, G. ;
Giordano, A. .
ONCOGENE, 2006, 25 (38) :5294-5301
[7]   IDENTIFICATION OF HERPESVIRUS-LIKE DNA-SEQUENCES IN AIDS-ASSOCIATED KAPOSIS-SARCOMA [J].
CHANG, Y ;
CESARMAN, E ;
PESSIN, MS ;
LEE, F ;
CULPEPPER, J ;
KNOWLES, DM ;
MOORE, PS .
SCIENCE, 1994, 266 (5192) :1865-1869
[8]   Merkel cell carcinoma and HIV infection [J].
Engels, EA ;
Frisch, M ;
Goedert, JJ ;
Biggar, RJ ;
Miller, RW .
LANCET, 2002, 359 (9305) :497-498
[9]  
Feng HC, 2008, SCIENCE, V319, P1096, DOI 10.1126/science.1152586
[10]   Human transcriptome subtraction by using short sequence tags to search for tumor viruses in conjunctival carcinoma [J].
Feng, Huichen ;
Taylor, Jennifer L. ;
Benos, Panayiotis V. ;
Newton, Robert ;
Waddell, Keith ;
Lucas, Sebastien B. ;
Chang, Yuan ;
Moore, Patrick S. .
JOURNAL OF VIROLOGY, 2007, 81 (20) :11332-11340