Nonlinear effects in Rh-catalyzed asymmetric olefin hydrogenation using mixtures of chiral monodentate P ligands

被引：41

作者：

Reetz, MT ^{[1
]}

Fu, Y ^{[1
]}

Meiswinkel, A ^{[1
]}

机构：

[1] Max Planck Inst Kohlenforsch, D-45470 Mulheim, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 09期

关键词：

asymmetric catalysis; hydrogenation; kinetics; nonlinear effects; rhodium;

D O I：

10.1002/anie.200503604

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Well mixed: A 1:1 mixture of two different binaphthol-derived monophosphonite ligands (L) is employed in the Rh-catalyzed hydrogenation of prochiral olefins (see scheme; cod = cyclooctadiene). Variation of the enantiopurity of the ligands results in unusual nonlinear effects; furthermore, > 92% ee can be achieved even if one component is racemic. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：1412 / 1415

页数：4

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