Growth factor control of pancreatic islet regeneration and function

被引：58

作者：

Assmann, Anke

Hinault, Charlotte

Kulkarni, Rohit N. ^{[1
]}

机构：

[1] Harvard Univ, Sch Med, Div Res, Joslin Diabet Ctr, Boston, MA 02215 USA

来源：

PEDIATRIC DIABETES | 2009年 / 10卷 / 01期

基金：

美国国家卫生研究院;

关键词：

aging; cell cycle; islets; obesity; regeneration; T1D and T2D; BETA-CELL MASS; INSULIN-RECEPTOR SUBSTRATE-2; GLUCAGON-LIKE PEPTIDE-1; EMBRYONIC STEM-CELLS; DEPENDENT DIABETES-MELLITUS; MICE LACKING INSULIN; K-ATP CHANNEL; GENE-EXPRESSION; FACTOR-I; TRANSCRIPTION FACTOR;

D O I：

10.1111/j.1399-5448.2008.00468.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Assmann A, Hinault C, Kulkarni RN. Growth factor control of pancreatic islet regeneration and function.Pediatric Diabetes 2009: 10: 14-32.

引用

收藏

页码：14 / 32

页数：19

相关论文

共 233 条

[1] Early neonatal death in mice homozygous for a null allele of the insulin receptor gene [J].

Accili, D ;

Drago, J ;

Lee, EJ ;

Johnson, MD ;

Cool, MH ;

Salvatore, P ;

Asico, LD ;

Jose, PA ;

Taylor, SI ;

Westphal, H .

NATURE GENETICS, 1996, 12 (01) :106-109

[2] Molecular regulation of pancreatic β-cell mass development, maintenance, and expansion [J].

Ackermann, Amanda M. ;

Gannon, Maureen .

JOURNAL OF MOLECULAR ENDOCRINOLOGY, 2007, 38 (1-2) :193-206

[3]

Ahlgren U, 1996, DEVELOPMENT, V122, P1409

[4] Glucose infusion in mice -: A new model to induce β-cell replication [J].

Alonso, Laura C. ;

Yokoe, Takuya ;

Zhang, Pili ;

Scott, Donald K. ;

Kim, Seung K. ;

O'Donnell, Christopher P. ;

Garcia-Ocana, Adolfo .

DIABETES, 2007, 56 (07) :1792-1801

[5] ALTERNATIVE PATHWAY OF INSULIN SIGNALING IN MICE WITH TARGETED DISRUPTION OF THE IRS-1 GENE [J].

ARAKI, E ;

LIPES, MA ;

PATTI, ME ;

BRUNING, JC ;

HAAG, B ;

JOHNSON, RS ;

KAHN, CR .

NATURE, 1994, 372 (6502) :186-190

[6] ADENOSINE 5'-TRIPHOSPHATE-SENSITIVE POTASSIUM CHANNELS [J].

ASHCROFT, FM .

ANNUAL REVIEW OF NEUROSCIENCE, 1988, 11 :97-118

[7] Roles of insulin receptor substrate-1, phosphatidylinositol 3-kinase, and release of intracellular Ca2+ stores in insulin-stimulated insulin secretion in β-cells [J].

Aspinwall, CA ;

Qian, WJ ;

Roper, MG ;

Kulkarni, RN ;

Kahn, CR ;

Kennedy, RT .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (29) :22331-22338

[8] Insulin stimulates primary β-cell proliferation via Raf-1 kinase [J].

Beith, Jennifer L. ;

Alejandro, Emilyn U. ;

Johnson, James D. .

ENDOCRINOLOGY, 2008, 149 (05) :2251-2260

[9] Islet β cell expression of constitutively active Akt1/PKBα induces striking hypertrophy, hyperplasia, and hyperinsulinemia [J].

Bernal-Mizrachi, E ;

Wen, W ;

Stahlhut, S ;

Welling, CM ;

Permutt, MA .

JOURNAL OF CLINICAL INVESTIGATION, 2001, 108 (11) :1631-1638

[10] Defective insulin secretion and increased susceptibility to experimental diabetes are induced by reduced Akt activity in pancreatic islet β cells [J].

Bernal-Mizrachi, E ;

Fatrai, S ;

Johnson, JD ;

Ohsugi, M ;

Otani, K ;

Han, ZQ ;

Polonsky, KS ;

Permutt, MA .

JOURNAL OF CLINICAL INVESTIGATION, 2004, 114 (07) :928-936

← 1 2 3 4 5 6 7 8 9 10 →