Opinion - The influence of bio-behavioural factors on tumour biology: pathways and mechanisms

被引：745

作者：

Antoni, MH

Lutgendorf, SK

Cole, SW

Dhabhar, FS

Sephton, SE

McDonald, PG

Stefanek, M

Sood, AK

机构：

[1] NCI, Basic & Biobehav Res Branch, Behav Res Program, Div Canc Control & Populat Sci,NIH, Bethesda, MD 20892 USA

[2] Univ Miami, Dept Psychol, Coral Gables, FL 33124 USA

[3] Univ Miami, Dept Psychiat, Coral Gables, FL 33124 USA

[4] Univ Miami, Dept Behav Sci, Coral Gables, FL 33124 USA

[5] Univ Miami, Sylvestor Canc Ctr, Coral Gables, FL 33124 USA

[6] Univ Iowa, Dept Psychol, Iowa City, IA 52242 USA

[7] Univ Iowa, Dept Obstet & Gynecol, Iowa City, IA 52242 USA

[8] Univ Iowa, Holden Comprehens Canc Ctr, Iowa City, IA 52242 USA

[9] Univ Calif Los Angeles, Sch Med, Div Hematol Oncol, Los Angeles, CA 90095 USA

[10] Stanford Univ, Dept Psychiat & Behav Sci, Sch Med, Off 2325, Stanford, CA 94305 USA

[11] Univ Louisville, Dept Psychol & Brain Sci, James Graham Brown Canc Ctr, Louisville, KY 40202 USA

[12] Univ Texas, MD Anderson Canc Ctr, Dept Gynecol Oncol, Unit 1362, Houston, TX 77230 USA

[13] Univ Texas, MD Anderson Canc Ctr, Dept Canc Biol, Unit 1362, Houston, TX 77230 USA

来源：

NATURE REVIEWS CANCER | 2006年 / 6卷 / 03期

关键词：

D O I：

10.1038/nrc1820

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

Epidemiological studies indicate that stress, chronic depression and lack of social support might serve as risk factors for cancer development and progression. Recent cellular and molecular studies have identified biological processes that could potentially mediate such effects. This review integrates clinical, cellular and molecular studies to provide a mechanistic understanding of the interface between biological and behavioural influences in cancer, and identifies novel behavioural or pharmacological interventions that might help improve cancer outcomes.

引用

页码：240 / 248

页数：9

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