Resolution of BIPHEP on Rh with a chiral diene auxiliary

被引：23

作者：

Faller, J. W. ^{[1
]}

Wilt, Jeremy C. ^{[1
]}

机构：

[1] Yale Univ, Dept Chem, New Haven, CT 06520 USA

来源：

JOURNAL OF ORGANOMETALLIC CHEMISTRY | 2006年 / 691卷 / 10期

关键词：

asymmetric catalysis; resolution; chiral induction;

D O I：

10.1016/j.jorganchem.2005.09.050

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Resolution of the atropisomeric chiral BIPHEP ligand on Rh has been achieved with the aid of 2-(4-tert-butyl-phenyl)-8-methoxy-1,8-dimethyl-bicyclo[2,2,2]octa-2,5-diene, a chiral chelating diene ligand. The diene complex 3 containing an (S)-BIPHEP ligand was found to be configurationally stable in CDCl3 solution at RT. Conversion of the diene complex 3 to a dicarbonyl Rh complex 4 that had a barrier of 25.0 kcal/mol for atropisomerization of the BIPHEP ligand. Preliminary studies of the use of the resolved complex 3 for catalysis are presented. (c) 2005 Elsevier B.V. All rights reserved.

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收藏

页码：2207 / 2212

页数：6

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