Biosensing and Probing of Intracellular Metabolic Pathways by NADH-Sensitive Quantum Dots

被引：113

作者：

Freeman, Ronit

Gill, Ron

Shweky, Itzhak

Kotler, Moshe

Banin, Uri

Willner, Itamar ^{[1
]}

机构：

[1] Hebrew Univ Jerusalem, Inst Chem, IL-91904 Jerusalem, Israel

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2009年 / 48卷 / 02期

基金：

以色列科学基金会;

关键词：

biosensors; enzymes; nanobiotechnology; nanoparticles; quantum dots; RESONANCE ENERGY-TRANSFER; NAD(P)(+)-DEPENDENT ENZYMES; AMPEROMETRIC BIOSENSORS; NAD(P)H COFACTORS; ELECTRODES; NANOPARTICLES; SENSORS; TRANSFORMATIONS; NANOCRYSTALS;

D O I：

10.1002/anie.200803421

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) On the blue Nile: NAD(P)H-sensitive Nile Blue functionalized CdSe/ZnS quantum dots have been developed for the optical sensing of biocatalytic processes involving NAD+-dependent enzymes and the screening of anticancer drugs by monitoring intracellular metabolism (see picture). © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.

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收藏

页码：309 / 313

页数：5

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