A highly active Suzuki catalyst for the synthesis of sterically hindered biaryls: Novel ligand coordination

被引：500

作者：

Yin, JJ ^{[1
]}

Rainka, MP ^{[1
]}

Zhang, XX ^{[1
]}

Buchwald, SL ^{[1
]}

机构：

[1] MIT, Dept Chem, Cambridge, MA 02139 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2002年 / 124卷 / 07期

关键词：

D O I：

10.1021/ja017082r

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A catalyst system for the preparation of biaryls containing four ortho substituents via Suzuki coupling is described. The combination of a catalytic quantity of Pd2(dba)3 with either an electron-rich biarylphosphine or DPEPhos is effective using a wide range of substrates. The X-ray crystal structure of (dba)Pd(2-(9-phenanthryl)phenyl-dicyclohexylphosphine), in which the Pd is coordinated to the 9,10-double bond of the phenanthryl group, is also reported. Copyright © 2002 American Chemical Society.

引用

页码：1162 / 1163

页数：2