Novel and efficient one-pot tandem synthesis of 2-styryl-substituted 4(3H)-quinazolinones

被引:49
作者
Dabiri, Minoo [1 ]
Baghbanzadeh, Mostafa [1 ]
Delbari, Akram Sadat [1 ]
机构
[1] Shahid Beheshti Univ, Dept Chem, Fac Sci, Tehran, Iran
来源
JOURNAL OF COMBINATORIAL CHEMISTRY | 2008年 / 10卷 / 05期
关键词
D O I
10.1021/cc800067g
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
A novel one-pot tandem synthesis of 2-styryl-4(3H)-quinazolinones in an acidic ionic liquid is reported. In this procedure isatoic anhydride, a primary aniline or ammonium acetate, and triethylorthoacetate are reacted in the presence of imidazolium trifluoroacetate [Hmim]TFA. Subsequently an aromatic aldehyde is added to the mixture to afford the title compounds in high to excellent yields.
引用
收藏
页码:700 / 703
页数:4
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