Synthesis of quinazolinones and quinazolines

被引：643

作者：

Connolly, DJ ^{[1
]}

Cusack, D ^{[1
]}

O'Sullivan, TP ^{[1
]}

Guiry, PJ ^{[1
]}

机构：

[1] Univ Coll Dublin, Conway Inst Biomol & Biomed Sci, Dept Chem, Ctr Synth & Chem Biol, Dublin 4, Ireland

来源：

TETRAHEDRON | 2005年 / 61卷 / 43期

关键词：

quinazolinones; quinazolines; luotonins; rutaecarpine;

D O I：

10.1016/j.tet.2005.07.010

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

(Chemical presented) Synthetic methods for the construction of the 4(3H)-quinazolinone 1 and quinazoline 2 skeletons, with a particular emphasis on the 2-substituted and 2,4-disubstituted analogues, are reviewed. The report contains 127 references. © 2005 Elsevier Ltd. All rights reserved.

引用

页码：10153 / 10202

页数：50

共 125 条

[1] A novel method for the synthesis of 4(3H)-quinazolinones [J].

Abdel-Jalil, RJ ;

Voelter, W ;

Saeed, M .

TETRAHEDRON LETTERS, 2004, 45 (17) :3475-3476

[2] PALLADIUM COMPLEX-CATALYZED INTERMOLECULAR REDUCTIVE N-HETEROCYCLIZATION - NOVEL SYNTHESIS OF QUINAZOLINE DERIVATIVES FROM 2-NITROBENZALDEHYDE OR 2-NITROPHENYL KETONES WITH FORMAMIDE [J].

AKAZOME, M ;

YAMAMOTO, J ;

KONDO, T ;

WATANABE, Y .

JOURNAL OF ORGANOMETALLIC CHEMISTRY, 1995, 494 (1-2) :229-233

[3] Novel series of 8H-quinazolino[4,3-b]quinazolin-8-ones via two Niementowski condensations [J].

Alexandre, FR ;

Berecibar, A ;

Wrigglesworth, R ;

Besson, T .

TETRAHEDRON, 2003, 59 (09) :1413-1419

[4] BRONCHODILATOR ALKALOID (VASICINONE) FROM ADHATODA-VASICA NEES [J].

AMIN, AH ;

MEHTA, DR .

NATURE, 1959, 184 (4695) :1317-1317

[5]

Armarego W. M. F., 1967, FUSED PYRIMIDINES 1

[6] Rearrangement of 4-imino-(1H,4H)-3,1-benzoxazine-2-ones to 2,4-quinazolinediones via an isocyanate carboxamide intermediate [J].

Azizian, J ;

Mehrdad, M ;

Jadidi, K ;

Sarrafi, Y .

TETRAHEDRON LETTERS, 2000, 41 (27) :5265-5268

[7] NONCLASSICAL ANTIMETABOLITES .10. FACILE SYNTHESIS OF 4-QUINAZOLONE-2-CARBOXYLIC ACID AND STRUCTURE OF BOGERTS AMMONIUM SALT [J].

BAKER, BR ;

ALMAULA, PI .

JOURNAL OF ORGANIC CHEMISTRY, 1962, 27 (12) :4672-&

[8] Synthesis of quinazolin-4-(3H)-ones from o-amidobenzonitriles using urea hydrogen peroxide [J].

Bandgar, BP .

SYNTHETIC COMMUNICATIONS, 1997, 27 (12) :2065-2068

[9] Studies leading to the identification of ZD1839 (Iressa™):: An orally active, selective epidermal growth factor receptor tyrosine kinase inhibitor targeted to the treatment of cancer [J].

Barker, AJ ;

Gibson, KH ;

Grundy, W ;

Godfrey, AA ;

Barlow, JJ ;

Healy, MP ;

Woodburn, JR ;

Ashton, SE ;

Curry, BJ ;

Scarlett, L ;

Henthorn, L ;

Richards, L .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2001, 11 (14) :1911-1914

[10]

BATVETSIAS V, 1998, SYNTHETIC COMMUN, V28, P4547

← 1 2 3 4 5 6 7 8 9 10 →