A Selective Fluoroionophore Based on BODIPY-functionalized Magnetic Silica Nanoparticles: Removal of Pb2+ from Human Blood

被引:177
作者
Lee, Hye Young [1 ]
Bae, Doo Ri [1 ]
Park, Ji Chan [2 ,3 ]
Song, Hyunjoon [2 ,3 ]
Han, Won Seok [1 ]
Jung, Jong Hwa [1 ]
机构
[1] Gyeongsang Natl Univ, Dept Chem & Res, Inst Nat Sci & Environm Biotechnol, Natl Core Res Ctr, Jinju 660701, South Korea
[2] Korea Adv Inst Sci & Technol, Dept Chem, Taejon 305701, South Korea
[3] Korea Adv Inst Sci & Technol, Sch Mol Sci, Taejon 305701, South Korea
关键词
blood; chemosensors; fluorescence; lead; nanoparticles; FLUORESCENT CHEMOSENSOR; SUPRAMOLECULAR CHEMISTRY; LEAD IONS; DERIVATIVES; BIOSENSOR; SWITCHES; BACTERIA; SENSORS; PROTEIN; SYSTEM;
D O I
10.1002/anie.200804714
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Get the lead out: The title fluorescence receptor exhibits a high affinity and selectivity for Pb2+ over competing metal ions in water (see picture) with an overall emission change of approximately 8-fold at the emission maximum for Pb2+. The fluorescence receptor can remove 96 % of 100 ppb Pb2+ from human blood, and can be useful and effective for the selective and rapid removal of Pb2+ in vivo. © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:1239 / 1243
页数:5
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