The asymmetric reduction of ketones using chiral ammonium fluoride salts and silanes

被引：42

作者：

Drew, MD

Lawrence, NJ

Watson, W

Bowles, SA

机构：

[1] UNIV MANCHESTER,INST SCI & TECHNOL,DEPT CHEM,MANCHESTER M60 1QD,LANCS,ENGLAND

[2] LANCASTER SYNTH LTD,MORECAMBE LA3 3DY,LANCS,ENGLAND

[3] BRITISH BIOTECH,OXFORD OX4 5LY,ENGLAND

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 33期

基金：

英国工程与自然科学研究理事会;

关键词：

D O I：

10.1016/S0040-4039(97)01445-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Acetophenone and substituted arylalkyl ketones are reduced with moderate to good enantioselectivity by silanes bearing alkoxyl or siloxy groups and chiral ammonium fluoride salts derived from cinchona alkaloids. (C) 1997 Elsevier Science Ltd.

引用

页码：5857 / 5860

页数：4

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