Nuclear organization of pre-mRNA splicing factors

被引：78

作者：

Sleeman, JE ^{[1
]}

Lamond, AI ^{[1
]}

机构：

[1] Univ Dundee, Inst Med Sci, Dept Biochem, Dundee DD1 5EH, Scotland

来源：

CURRENT OPINION IN CELL BIOLOGY | 1999年 / 11卷 / 03期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/S0955-0674(99)80052-0

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The splicing of mRNA precursors (pre-mRNA) in the nucleus is catalyzed by a complex machinery termed the spliceosome. In order to understand how it functions in vivo, it is essential to complement biochemical analyses with a detailed study of how spliceosome components are organized within the nucleus.

引用

页码：372 / 377

页数：6

共 62 条

[1] Isolation and characterization of PNUTS, a putative protein phosphatase 1 nuclear targeting subunit [J].

Allen, PB ;

Kwon, YG ;

Nairn, AC ;

Greengard, P .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (07) :4089-4095

[2] Protein heterogeneity in the coiled body compartment [J].

Alliegro, MC ;

Alliegro, MA .

EXPERIMENTAL CELL RESEARCH, 1998, 239 (01) :60-68

[3] Coilin can form a complex with the U7 small nuclear ribonucleoprotein [J].

Bellini, M ;

Gall, JG .

MOLECULAR BIOLOGY OF THE CELL, 1998, 9 (10) :2987-3001

[4] MUTATIONAL ANALYSIS OF P80 COILIN INDICATES A FUNCTIONAL INTERACTION BETWEEN COILED BODIES AND THE NUCLEOLUS [J].

BOHMANN, K ;

FERREIRA, JA ;

LAMOND, AI .

JOURNAL OF CELL BIOLOGY, 1995, 131 (04) :817-831

[5]

Bohmann K, 1995, J CELL SCI, P107

[6]

Boudonck K, 1998, J CELL SCI, V111, P3687

[7]

BROSI R, 1993, J BIOL CHEM, V268, P17640

[8] HISTONE GENES ARE LOCATED AT THE SPHERE LOCI OF XENOPUS LAMPBRUSH CHROMOSOMES [J].

CALLAN, HG ;

GALL, JG ;

MURPHY, C .

CHROMOSOMA, 1991, 101 (04) :245-251

[9] The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intranuclear distribution [J].

Colwill, K ;

Pawson, T ;

Andrews, B ;

Prasad, J ;

Manley, JL ;

Bell, JC ;

Duncan, PI .

EMBO JOURNAL, 1996, 15 (02) :265-275

[10] Changes in the nucleolar and coiled body compartments precede lamina and chromatin reorganization during fibre cell denucleation in the bovine lens [J].

Dahm, R ;

Gribbon, C ;

Quinlan, RA ;

Prescott, AR .

EUROPEAN JOURNAL OF CELL BIOLOGY, 1998, 75 (03) :237-246

← 1 2 3 4 5 6 7 →