Nuclear organization of pre-mRNA splicing factors

被引:78
作者
Sleeman, JE [1 ]
Lamond, AI [1 ]
机构
[1] Univ Dundee, Inst Med Sci, Dept Biochem, Dundee DD1 5EH, Scotland
基金
英国惠康基金;
关键词
D O I
10.1016/S0955-0674(99)80052-0
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The splicing of mRNA precursors (pre-mRNA) in the nucleus is catalyzed by a complex machinery termed the spliceosome. In order to understand how it functions in vivo, it is essential to complement biochemical analyses with a detailed study of how spliceosome components are organized within the nucleus.
引用
收藏
页码:372 / 377
页数:6
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