A New Development in Senescence

被引:53
作者
Banito, Ana [1 ]
Lowe, Scott W. [1 ,2 ]
机构
[1] Mem Sloan Kettering Canc Ctr, New York, NY 10065 USA
[2] Howard Hughes Med Inst, New York, NY 10065 USA
关键词
FIBROSIS; CANCER;
D O I
10.1016/j.cell.2013.10.050
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
070307 [化学生物学]; 071010 [生物化学与分子生物学];
摘要
Cellular senescence is implicated in several pathological responses in the adult, with important repercussions in tumor suppression, wound healing, and aging. Two studies by Munoz-Espin et al. and Storer et al. now reveal that senescence contributes to embryonic development, suggesting a primordial role in normal physiology.
引用
收藏
页码:977 / 978
页数:2
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