Serotonin transporter gene promoter region polymorphism associated with poststroke major depression

被引：63

作者：

Ramasubbu, R ^{[1
]}

Tobias, R ^{[1
]}

Buchan, AM ^{[1
]}

Bech-Hansen, NT ^{[1
]}

机构：

[1] Univ Calgary, Dept Psychiat & Clin Neurosci, Calgary, AB T2N 2T9, Canada

来源：

JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES | 2006年 / 18卷 / 01期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1176/appi.neuropsych.18.1.96

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The authors examined variations of serotonin transporter-linked promoter region (5-HTTLPR) functional polymorphism in 26 stroke patients with major depression and in 25 unrelated nondepressed stroke subjects of Caucasian descent. Findings indicate a significant association between 5-HTTLPR short variant genotype and poststroke major depression.

引用

页码：96 / 99

页数：4

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