Molecular epidemiology of dengue virus type 3 in Northern South America: 2000-2005

被引：31

作者：

Kochel, Tadeusz ^{[1
,2
]}

Aguilar, Patricia ^{[1
,2
]}

Felices, Vidal ^{[1
,2
]}

Comach, Guillermo ^{[3
]}

Cruz, Cristopher ^{[1
,2
]}

Alava, Aracely ^{[4
]}

Vargas, Jorge ^{[5
]}

Olson, James ^{[1
,2
]}

Blair, Patrick ^{[1
,2
]}

机构：

[1] USN, Med Res Ctr Detachment, Unit 3800, APO, AA 34031 USA

[2] Amer Embassy, Lima, Peru

[3] BIOMED UC, Lab Reg Diagnost & Invest Dengue & Otras Enfermed, Maracay 2105, Estado Arague, Venezuela

[4] Inst Nacl Higiene & Med Trop Leopoldo Izquieta Pe, Guayaquil, Ecuador

[5] Ctr Nacl Enfermedades Trop, Santa Cruz, Bolivia

来源：

INFECTION GENETICS AND EVOLUTION | 2008年 / 8卷 / 05期

关键词：

Dengue-3; virus; evolution; transmission;

D O I：

10.1016/j.meegid.2008.06.008

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

A phylogenetic approach was used to identify genetic variants of DENV-3 subtype III that may have emerged during or after its expansion throughout South America. We sequenced the capsid, premembrane/membrane and envelope genes from 22 DENV-3 strains isolated from Venezuela, Bolivia, Ecuador and Peru between 2000 and 2005. Phylogenetic analysis showed that the isolates sequenced in this study formed three clades within subtype III: one with the isolates from Venezuela, one with the Bolivian isolates and one with the isolates from Ecuador and Peru. (C) 2008 Elsevier B.V. All rights reserved.

引用

页码：682 / 688

页数：7

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