The protein structure initiative structural genomics knowledgebase

被引:72
作者
Berman, Helen M. [1 ]
Westbrook, John D. [1 ]
Gabanyi, Margaret J. [1 ]
Tao, Wendy [1 ]
Shah, Raship [1 ]
Kouranov, Andrei [1 ]
Schwede, Torsten [2 ,3 ]
Arnold, Konstantin [2 ,3 ]
Kiefer, Florian [2 ,3 ]
Bordoli, Lorenza [2 ,3 ]
Kopp, Jrgen [2 ,3 ,4 ]
Podvinec, Michael [2 ,3 ]
Adams, Paul D. [5 ]
Carter, Lester G. [5 ]
Minor, Wladek [6 ]
Nair, Rajesh [7 ]
Baer, Joshua La [8 ,9 ]
机构
[1] Rutgers State Univ, Dept Chem & Chem Biol, Piscataway, NJ 08854 USA
[2] Univ Basel, Swiss Inst Bioinformat, CH-4056 Basel, Switzerland
[3] Univ Basel, Biozentrum, CH-4056 Basel, Switzerland
[4] Heidelberg Univ, Biochem Zentrum, D-69120 Heidelberg, Germany
[5] Univ Calif Berkeley, Lawrence Berkeley Natl Lab, Phys Biosci Div, Berkeley, CA 94720 USA
[6] Univ Virginia, Dept Mol Physiol & Biol Phys, Charlottesville, VA 22908 USA
[7] Columbia Univ, Dept Biochem & Mol Biophys, New York, NY 10027 USA
[8] Harvard Univ, Sch Med, Harvard Inst Proteom, Boston, MA 02115 USA
[9] Harvard Univ, Sch Med, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA
基金
美国国家卫生研究院;
关键词
DATABASE; CLASSIFICATION; MODELS;
D O I
10.1093/nar/gkn790
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The Protein Structure Initiative Structural Genomics Knowledgebase (PSI SGKB, http://kb.psi-structural genomics.org) has been created to turn the products of the PSI structural genomics effort into knowledge that can be used by the biological research community to understand living systems and disease. This resource provides central access to structures in the Protein Data Bank (PDB), along with functional annotations, associated homology models, worldwide protein target tracking information, available protocols and the potential to obtain DNA materials for many of the targets. It also offers the ability to search all of the structural and methodological publications and the innovative technologies that were catalyzed by the PSI's high-throughput research efforts. In collaboration with the Nature Publishing Group, the PSI SGKB provides a research library, editorials about new research advances, news and an events calendar to present a broader view of structural biology and structural genomics. By making these resources freely available, the PSI SGKB serves as a bridge to connect the structural biology and the greater biomedical communities.
引用
收藏
页码:D365 / D368
页数:4
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