Fluorine in medicinal chemistry: A review of anti-cancer agents

被引:1057
作者
Isanbor, C [1 ]
O'Hagan, D
机构
[1] Univ Lagos, Dept Chem, Lagos, Nigeria
[2] Univ St Andrews, Sch Chem, St Andrews KY16 9ST, Fife, Scotland
[3] Univ St Andrews, Ctr Biomol Sci, St Andrews KY16 9ST, Fife, Scotland
关键词
pharmaceutical; fluoro-substituent; drug; prodrug; anti-cancer agent;
D O I
10.1016/j.jfluchem.2006.01.011
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
In this review those fluorinated compounds which have found a role as anti-cancer agents are summarized. The emphasis is to highlight the important drugs but also to highlight the latest developments on emerging compounds. This has been done as comprehensively as possible with the objective of informing readers of some of the latest developments in this area. (c) 2006 Elsevier B.V. All rights reserved.
引用
收藏
页码:303 / 319
页数:17
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