Protective mechanisms against toxic electrophiles in Escherichia coli

被引：48

作者：

Ferguson, GP ^{[1
]}

机构：

[1] Univ Aberdeen, Inst Med Sci, Dept Cell & Mol Biol, Aberdeen AB25 2ZD, Scotland

来源：

TRENDS IN MICROBIOLOGY | 1999年 / 7卷 / 06期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/S0966-842X(99)01510-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Escherichia coli are exposed to toxic electrophiles from both endogenous and exogenous sources. To survive, E. coli have developed novel protective mechanisms that appear unique to bacteria. In the absence of one of these mechanisms, electrophiles induce rapid killing. Hence it appears that electrophile-protective mechanisms represent novel targets for antibacterial drug research.

引用

页码：242 / 247

页数：6

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