Global transmission of influenza viruses from humans to swine

被引：140

作者：

Nelson, Martha I. ^{[1
]}

Gramer, Marie R. ^{[2
]}

Vincent, Amy L. ^{[3
]}

Holmes, Edward C. ^{[1
,4
]}

机构：

[1] NIH, Fogarty Int Ctr, Bethesda, MD 20892 USA

[2] Univ Minnesota, Vet Diagnost Lab, St Paul, MN 55108 USA

[3] USDA ARS, Virus & Prion Dis Res Unit, Natl Anim Dis Ctr, Ames, IA 50010 USA

[4] Penn State Univ, Dept Biol, Ctr Infect Dis Dynam, University Pk, PA 16802 USA

来源：

JOURNAL OF GENERAL VIROLOGY | 2012年 / 93卷

关键词：

PANDEMIC H1N1 2009; A VIRUSES; PIGS; REASSORTMENT; ORIGIN; OUTBREAK; ARGENTINA; FARM;

D O I：

10.1099/vir.0.044974-0

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

To determine the extent to which influenza viruses jump between human and swine hosts, we undertook a large-scale phylogenetic analysis of pandemic A/H1N1/09 (H1N1pdm09) influenza virus genome sequence data. From this, we identified at least 49 human-to-swine transmission events that occurred globally during 2009-2011, thereby highlighting the ability of the H1N1pdm09 virus to transmit repeatedly from humans to swine, even following adaptive evolution in humans. Similarly, we identified at least 23 separate introductions of human seasonal (non-pandemic) H1 and H3 influenza viruses into swine globally since 1990. Overall, these results reveal the frequency with which swine are exposed to human influenza viruses, indicate that humans make a substantial contribution to the genetic diversity of influenza viruses in swine, and emphasize the need to improve biosecurity measures at the human swine interface, including influenza vaccination of swine workers.

引用

页码：2195 / 2203

页数：9

共 26 条

[1] The influenza virus resource at the national center for biotechnology information [J].

Bao, Yiming ;

Bolotov, Pavel ;

Dernovoy, Dmitry ;

Kiryutin, Boris ;

Zaslavsky, Leonid ;

Tatusova, Tatiana ;

Ostell, Jim ;

Lipman, David .

JOURNAL OF VIROLOGY, 2008, 82 (02) :596-601

[2] Outbreak of swine influenza in Argentina reveals a non-contemporary human H3N2 virus highly transmissible among pigs [J].

Cappuccio, Javier A. ;

Pena, Lindomar ;

Dibarbora, Marina ;

Rimondi, Agustina ;

Pineyro, Pablo ;

Insarralde, Lucas ;

Ouiroga, Maria A. ;

Machuca, Mariana ;

Craig, Maria I. ;

Olivera, Valeria ;

Chockalingam, Ashok ;

Perfumo, Carlos J. ;

Perez, Daniel R. ;

Pereda, Ariel .

JOURNAL OF GENERAL VIROLOGY, 2011, 92 :2871-2878

[3]

Centers for Disease Control and Prevention (CDC), 2012, MMWR Morb Mortal Wkly Rep, V60, P1741

[4] BEAST: Bayesian evolutionary analysis by sampling trees [J].

Drummond, Alexei J. ;

Rambaut, Andrew .

BMC EVOLUTIONARY BIOLOGY, 2007, 7 (1)

[5] Multiple Reassortment between Pandemic (H1N1) 2009 and Endemic Influenza Viruses in Pigs, United States [J].

Ducatez, Mariette F. ;

Hause, Ben ;

Stigger-Rosser, Evelyn ;

Darnell, Daniel ;

Corzo, Cesar ;

Juleen, Kevin ;

Simonson, Randy ;

Brockwell-Staats, Christy ;

Rubrum, Adam ;

Wang, David ;

Webb, Ashley ;

Crumpton, Jeri-Carol ;

Lowe, James ;

Gramer, Marie ;

Webby, Richard J. .

EMERGING INFECTIOUS DISEASES, 2011, 17 (09) :1624-1629

[6] Antigenic and Genetic Characteristics of Swine-Origin 2009 A(H1N1) Influenza Viruses Circulating in Humans [J].

Garten, Rebecca J. ;

Davis, C. Todd ;

Russell, Colin A. ;

Shu, Bo ;

Lindstrom, Stephen ;

Balish, Amanda ;

Sessions, Wendy M. ;

Xu, Xiyan ;

Skepner, Eugene ;

Deyde, Varough ;

Okomo-Adhiambo, Margaret ;

Gubareva, Larisa ;

Barnes, John ;

Smith, Catherine B. ;

Emery, Shannon L. ;

Hillman, Michael J. ;

Rivailler, Pierre ;

Smagala, James ;

de Graaf, Miranda ;

Burke, David F. ;

Fouchier, Ron A. M. ;

Pappas, Claudia ;

Alpuche-Aranda, Celia M. ;

Lopez-Gatell, Hugo ;

Olivera, Hiram ;

Lopez, Irma ;

Myers, Christopher A. ;

Faix, Dennis ;

Blair, Patrick J. ;

Yu, Cindy ;

Keene, Kimberly M. ;

Dotson, P. David, Jr. ;

Boxrud, David ;

Sambol, Anthony R. ;

Abid, Syed H. ;

George, Kirsten St. ;

Bannerman, Tammy ;

Moore, Amanda L. ;

Stringer, David J. ;

Blevins, Patricia ;

Demmler-Harrison, Gail J. ;

Ginsberg, Michele ;

Kriner, Paula ;

Waterman, Steve ;

Smole, Sandra ;

Guevara, Hugo F. ;

Belongia, Edward A. ;

Clark, Patricia A. ;

Beatrice, Sara T. ;

Donis, Ruben .

SCIENCE, 2009, 325 (5937) :197-201

[7] New Algorithms and Methods to Estimate Maximum-Likelihood Phylogenies: Assessing the Performance of PhyML 3.0 [J].

Guindon, Stephane ;

Dufayard, Jean-Francois ;

Lefort, Vincent ;

Anisimova, Maria ;

Hordijk, Wim ;

Gascuel, Olivier .

SYSTEMATIC BIOLOGY, 2010, 59 (03) :307-321

[8]

Hofshagen M, 2009, EUROSURVEILLANCE, V14, P15

[9] The first identified case of pandemic H1N1 influenza in pigs in Australia [J].

Holyoake, P. K. ;

Kirkland, P. D. ;

Davis, R. J. ;

Arzey, K. E. ;

Watson, J. ;

Lunt, R. A. ;

Wang, J. ;

Wong, F. ;

Moloney, B. J. ;

Dunn, S. E. .

AUSTRALIAN VETERINARY JOURNAL, 2011, 89 (11) :427-431

[10]

Howard WA, 2011, EMERG INFECT DIS, V17, P1049, DOI [10.3201/eid1706.101886, 10.3201/eid/1706.101886]

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