DEVELOPMENT OF ADYNAMIC TEST PHANTOM FOR OPTICAL TOPOGRAPHY

被引:7
作者
Koh, Peck H. [1 ]
Elwell, Clare E. [1 ]
Delpy, David T. [1 ]
机构
[1] UCL, Dept Med Phys & Bioengn, London WC1E 6BT, England
来源
OXYGEN TRANSPORT TO TISSUE XXX | 2009年 / 645卷
基金
英国工程与自然科学研究理事会;
关键词
REPRODUCIBLE PHANTOM; SPECTROSCOPY; DESIGN;
D O I
10.1007/978-0-387-85998-9_22
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Optical topography (OT) is a near infrared spectroscopy (NIRS) technique that provides spatial maps of haemodynamic and oxygenation changes. When developing, testing and calibrating OT systems it is often necessary to use tissue simulating phantoms that are capable of providing realistic changes in attenuation properties. We present a novel dynamic tissue phantom that enables spatially and temporally varying tissue properties to be reproduced in a controlled manner. This new dynamic test phantom consists of a modified liquid crystal display (LCD) (enabling flexible and rapid changes in attenuation across different regions of the phantom) sandwiched between two layers Of tissue Simulating epoxy resin (providing static and homogeneous optical absorption and scattering). By activating different pixels in the liquid crystal display it is possible to produce highly localised and dynamic changes in attenuation which call be used to Simulate the changes associated with the cerebral haemodynamic response to functional activation. The reproducibility Of the dynamic phantom will be described with examples of its use with all OT system.
引用
收藏
页码:141 / 146
页数:6
相关论文
共 7 条
[1]   Tissue mimicking materials for a multi-imaging modality prostate phantom [J].
D'Souza, WD ;
Madsen, EL ;
Unal, O ;
Vigen, KK ;
Frank, GR ;
Thomadsen, BR .
MEDICAL PHYSICS, 2001, 28 (04) :688-700
[2]   Tissue-like phantoms for near-infrared fluorescence imaging system assessment and the training of surgeons [J].
De Grand, AM ;
Lomnes, SJ ;
Lee, DS ;
Pietrzykowski, M ;
Ohnishi, S ;
Morgan, TG ;
Gogbashian, A ;
Laurence, RG ;
Frangioni, JV .
JOURNAL OF BIOMEDICAL OPTICS, 2006, 11 (01)
[3]   A DESIGN FOR A STABLE AND REPRODUCIBLE PHANTOM FOR USE IN NEAR-INFRARED IMAGING AND SPECTROSCOPY [J].
FIRBANK, M ;
DELPY, DT .
PHYSICS IN MEDICINE AND BIOLOGY, 1993, 38 (06) :847-853
[4]   AN IMPROVED DESIGN FOR A STABLE AND REPRODUCIBLE PHANTOM MATERIAL FOR USE IN NEAR-INFRARED SPECTROSCOPY AND IMAGING [J].
FIRBANK, M ;
ODA, M ;
DELPY, DT .
PHYSICS IN MEDICINE AND BIOLOGY, 1995, 40 (05) :955-961
[5]   DEVELOPMENT OF A TISSUE-EQUIVALENT PHANTOM FOR DIAPHANOGRAPHY [J].
LINFORD, J ;
SHALEV, S ;
BEWS, J ;
BROWN, R ;
SCHIPPER, H .
MEDICAL PHYSICS, 1986, 13 (06) :869-875
[6]   A 32-channel time-resolved instrument for medical optical tomography [J].
Schmidt, FEW ;
Fry, ME ;
Hillman, EMC ;
Hebden, JC ;
Delpy, DT .
REVIEW OF SCIENTIFIC INSTRUMENTS, 2000, 71 (01) :256-265
[7]   Measurement system for noninvasive dynamic optical topography [J].
Yamashita, Y ;
Maki, A ;
Koizumi, H .
JOURNAL OF BIOMEDICAL OPTICS, 1999, 4 (04) :414-417