Simple highly modular acyclic amine-catalyzed direct enantioselective addition of ketones to nitro-olefins

被引：156

作者：

Xu, YM ^{[1
]}

Córdova, A ^{[1
]}

机构：

[1] Stockholm Univ, Dept Organ Chem, Arrhenius Lab, S-10691 Stockholm, Sweden

来源：

CHEMICAL COMMUNICATIONS | 2006年 / 04期

关键词：

D O I：

10.1039/b514783m

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Simple, highly modular primary amino acid derivatives catalyze the direct enantioselective addition of ketones to nitro-olefins with high stereocontrol and furnish the corresponding aldol products in high yield with up to > 38 : 1 dr and up to 99% ee.

引用

页码：460 / 462

页数：3

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