Epidemiology of Parkinson's disease

被引:267
作者
Alves, Guido [1 ,3 ]
Forsaa, Elin Bjelland [1 ,3 ]
Pedersen, Kenn Freddy [1 ,3 ]
Gjerstad, Michaela Dreetz [1 ,3 ]
Larsen, Jan Petter [1 ,2 ,3 ]
机构
[1] Stavanger Univ Hosp, Norwegian Ctr Movement Disorders, N-4068 Stavanger, Norway
[2] Univ Bergen, Sch Med, Inst Clin Med, N-5020 Bergen, Norway
[3] Stavanger Univ Hosp, Dept Neurol, N-4068 Stavanger, Norway
关键词
Parkinson's disease; epidemiology; population-based; progression;
D O I
10.1007/s00415-008-5004-3
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Epidemiological research aims to provide information on the development, prevalence and progression of diseases, and their associated risk factors. Epidemiological research is thus the basis of increasing our understanding on the aetiology of diseases and as a consequence the starting point for identifying at risk groups in the population, development for novel prevention and treatment strategies, and health care planning. This review provides an overview of the epidemiology of Parkinson's disease, the second most common neuro degenerative disorder, with special emphasis on population-based data on the clinical progression of motor and non-motor features of the disease.
引用
收藏
页码:18 / 32
页数:15
相关论文
共 184 条
[91]   Familial Parkinson's disease: a community-based study [J].
Kurz, M ;
Alves, G ;
Aarsland, D ;
Larsen, JP .
EUROPEAN JOURNAL OF NEUROLOGY, 2003, 10 (02) :159-163
[92]   Occupational and environmental risk factors for Parkinson's disease [J].
Lai, BCL ;
Marion, SA ;
Teschke, K ;
Tsui, JKC .
PARKINSONISM & RELATED DISORDERS, 2002, 8 (05) :297-309
[93]  
Larsen JP, 2000, MOVEMENT DISORD, V15, P826, DOI 10.1002/1531-8257(200009)15:5<826::AID-MDS1010>3.0.CO
[94]  
2-E
[95]   Higher incidence of depression preceding the onset of Parkinson's disease: A register study [J].
Leentjens, AFG ;
Van den Akker, M ;
Metsemakers, JFM ;
Lousberg, R ;
Verhey, FRJ .
MOVEMENT DISORDERS, 2003, 18 (04) :414-418
[96]   Deletions in the Parkin gene and genetic heterogeneity in a Greek family with early onset Parkinson's disease [J].
Leroy, E ;
Anastasopoulos, D ;
Konitsiotis, S ;
Lavedan, C ;
Polymeropoulos, MH .
HUMAN GENETICS, 1998, 103 (04) :424-427
[97]   Motor impairment in PD - Relationship to incident dementia and age [J].
Levy, G ;
Tang, MX ;
Cote, LJ ;
Louis, ED ;
Alfaro, B ;
Mejia, H ;
Stern, Y ;
Marder, K .
NEUROLOGY, 2000, 55 (04) :539-544
[98]   The association of incident dementia with mortality in PD [J].
Levy, G ;
Tang, MX ;
Louis, ED ;
Côté, LJ ;
Alfaro, B ;
Mejia, H ;
Stern, Y ;
Marder, K .
NEUROLOGY, 2002, 59 (11) :1708-1713
[99]   Combined effect of age and severity on the risk of dementia in Parkinson's disease [J].
Levy, G ;
Schupf, N ;
Tang, MX ;
Cote, LJ ;
Louis, ED ;
Mejia, H ;
Stern, Y ;
Marder, K .
ANNALS OF NEUROLOGY, 2002, 51 (06) :722-729
[100]   Apathy is not depression [J].
Levy, ML ;
Cummings, JL ;
Fairbanks, LA ;
Masterman, D ;
Miller, BL ;
Craig, AH ;
Paulsen, JS ;
Litvan, I .
JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES, 1998, 10 (03) :314-319