Trends in Aortic Valve Replacement for Elderly Patients in the United States, 1999-2011

被引:124
作者
Barreto-Filho, Jose Augusto [1 ,2 ,3 ]
Wang, Yun [3 ,4 ,5 ]
Dodson, John A. [6 ]
Desai, Mayur M. [7 ,8 ]
Sugeng, Lissa [5 ]
Geirsson, Arnar [9 ]
Krumholz, Harlan M. [3 ,5 ,8 ,10 ]
机构
[1] Univ Fed Sergipe, Div Cardiol, Aracaju, Sergipe, Brazil
[2] Clin & Hosp Sao Lucas, Aracaju, Sergipe, Brazil
[3] Yale New Haven Hosp, Ctr Outcomes Res & Evaluat, New Haven, CT 06504 USA
[4] Harvard Univ, Sch Publ Hlth, Dept Biostat, Boston, MA 02115 USA
[5] Yale Univ, Sch Med, Dept Internal Med, Sect Cardiovasc Med, New Haven, CT 06510 USA
[6] Brigham & Womens Hosp, Dept Internal Med, Div Aging, Boston, MA 02115 USA
[7] Yale Univ, Sch Publ Hlth, Dept Chron Dis Epidemiol, New Haven, CT 06510 USA
[8] Yale Univ, Sch Med, Robert Wood Johnson Clin Scholars Program, New Haven, CT 06510 USA
[9] Yale Univ, Sch Med, Sect Cardiac Surg, Dept Surg, New Haven, CT 06510 USA
[10] Yale Univ, Sch Publ Hlth, Dept Hlth Policy & Management, New Haven, CT 06510 USA
来源
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION | 2013年 / 310卷 / 19期
关键词
PROFILING HOSPITAL PERFORMANCE; VALVULAR HEART-DISEASE; ACC/AHA; 2006; GUIDELINES; ASSOCIATION TASK-FORCE; 30-DAY MORTALITY-RATES; QUALITY-OF-CARE; RACIAL DISPARITIES; MECHANICAL VALVE; SURGERY; MANAGEMENT;
D O I
10.1001/jama.2013.282437
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
IMPORTANCE There is a need to describe contemporary outcomes of surgical aortic valve replacement (AVR) as the population ages and transcatheter options emerge. OBJECTIVE To assess procedure rates and outcomes of surgical AVR over time. DESIGN, SETTING, AND PARTICIPANTS A serial cross-sectional cohort study of 82 755 924 Medicare fee-for-service beneficiaries undergoing AVR in the United States between 1999 and 2011. MAIN OUTCOMES AND MEASURES Procedure rates for surgical AVR alone and with coronary artery bypass graft (CABG) surgery, 30-day and 1-year mortality, and 30-day readmission rates. RESULTS The AVR procedure rate increased by 19 (95% CI, 19-20) procedures per 100 000 person-years over the 12-year period (P<.001), with an age-, sex-, and race-adjusted rate increase of 1.6% (95% CI, 1.0%-1.8%) per year. Mortality decreased at 30 days (absolute decrease, 3.4%; 95% CI, 3.0%-3.8%; adjusted annual decrease, 4.1%; 95% CI, 3.7%-4.4%) per year and at 1 year (absolute decrease, 2.6%; 95% CI, 2.1%-3.2%; adjusted annual decrease, 2.5%; 95% CI, 2.3%-2.8%). Thirty-day all-cause readmission also decreased by 1.1% (95% CI, 0.9%-1.3%) per year. Aortic valve replacement with CABG surgery decreased, women and black patients had lower procedure and higher mortality rates, and mechanical prosethetic implants decreased, but 23.9% of patients 85 years and older continued to receive a mechanical prosthesis in 2011. CONCLUSIONS AND RELEVANCE Between 1999 and 2011, the rate of surgical AVR for elderly patients in the United States increased and outcomes improved substantially. Medicare data preclude the identification of the causes of the findings and the trends in procedure rates and outcomes cannot be causally linked. Nevertheless, the findings may be a useful benchmark for outcomes with surgical AVR for older patients eligible for surgery considering newer transcatheter treatments.
引用
收藏
页码:2078 / 2085
页数:8
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