Nickel-catalyzed coupling of aryl iodides with aromatic aldehydes: Chemoselective synthesis of ketones

被引：136

作者：

Huang, YC ^{[1
]}

Majumdar, KK ^{[1
]}

Cheng, CH ^{[1
]}

机构：

[1] Natl Tsing Hua Univ, Dept Chem, Hsinchu 300, Taiwan

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2002年 / 67卷 / 05期

关键词：

D O I：

10.1021/jo010289i

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Aryl iodides (ArI) couple with aryl aldehydes (Ar'CHO) in the presence of Ni(dppe)Br-2 and Zn to give the corresponding biaryl ketones (ArCOAr'). The use of a bidentate phosphine complex is critical to the success of this catalytic reaction. The reaction provides a new procedure for the synthesis of various functionalized biaryl ketones.

引用

页码：1682 / 1684

页数：3

共 23 条

[21] REACTION OF ARYL AND VINYL HALIDES WITH ZEROVALENT NICKEL-PREPARATIVE ASPECTS AND THE SYNTHESIS OF ALNUSONE [J].