Ionic liquid promoted novel and efficient one pot synthesis of 3,4-dihydropyrimidin-2-(1H)-ones at ambient temperature under ultrasound irradiation

被引：153

作者：

Gholap, AR ^{[1
]}

Venkatesan, K ^{[1
]}

Daniel, T ^{[1
]}

Lahoti, RJ ^{[1
]}

Srinivasan, KV ^{[1
]}

机构：

[1] Natl Chem Lab, Organ Chem Technol Div, Pune 411008, Maharashtra, India

来源：

GREEN CHEMISTRY | 2004年 / 6卷 / 03期

关键词：

D O I：

10.1039/b314015f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

3,4-Dihydropyrimidin-2-(1H)-ones have been synthesized in excellent yields in short reaction time at ambient temperature in the absence of any added catalyst by the reaction of aromatic or aliphatic aldehydes with ethyl acetoacetate (EAA) and urea (or thiourea) in room temperature ionic liquid (IL) under ultrasound irradiation. The evidence for the role of IL in promoting this multicomponent reaction has been given. Based on this evidence, a plausible mechanistic pathway has been postulated.

引用

页码：147 / 150

页数：4

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