Synthesis of new acyclic nucleoside phosphonic acids by Michael addition

被引：24

作者：

Lazrek, HB ^{[1
]}

Khaider, H ^{[1
]}

Rochdi, A ^{[1
]}

Barascut, JL ^{[1
]}

Imbach, JL ^{[1
]}

机构：

[1] UNIV MONTPELLIER SCI & TECH LANGUEDOC 2,CHIM BIOORGAN LAB,URA 488 CNRS,F-34095 MONTPELLIER 5,FRANCE

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 27期

关键词：

D O I：

10.1016/0040-4039(96)00910-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

New acyclic nucleoside phosphonic acids in the purine and pyrimidine series were prepared via one step by Michael addition. These compounds are the first reported acyclonucleosides enamines which incorporate the alpha, beta-unsaturated phosphonic acid as a phosphate mimic. Copyright (C) 1996 Published by Elsevier Science Ltd

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页码：4701 / 4704

页数：4

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