Getting a GRIP on liprins

被引：10

作者：

Baran, R ^{[1
]}

Jin, YS

机构：

[1] Univ Calif Santa Cruz, Dept Mol Cell & Dev Biol, Santa Cruz, CA 95064 USA

[2] Univ Calif Santa Cruz, Howard Hughes Med Inst, Santa Cruz, CA 95064 USA

来源：

NEURON | 2002年 / 34卷 / 01期

关键词：

D O I：

10.1016/S0896-6273(02)00649-9

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Two papers in this issue of Neuron add a new dimension to our understanding of liprin and LAR RPTP function during synapse formation. Kaufmann et al. (2002) present evidence that Dliprin-α interacts with Dlar to regulate presynaptic morphogenesis of the Drosophila neuromuscular junction. Wyszynski et al. (2002) demonstrate that mammalian liprin-α1 forms a complex with the PDZ protein GRIP and LAR in both pre- and postsynaptic compartments of hippocampal neurons and is required for the clustering of the GluR2 glutamate receptor in dendritic spines.

引用

页码：1 / 2

页数：2

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