Comet: An open-source MS/MS sequence database search tool

被引：1048

作者：

Eng, Jimmy K. ^{[1
]}

Jahan, Tahmina A. ^{[1
]}

Hoopmann, Michael R. ^{[2
]}

机构：

[1] Univ Washington, Dept Genome Sci, Seattle, WA 98195 USA

[2] Inst Syst Biol, Seattle, WA USA

来源：

PROTEOMICS | 2013年 / 13卷 / 01期

关键词：

Bioinformatics; Identification; Peptide; Protein; MS; PEPTIDE IDENTIFICATION; STATISTICAL-MODEL; PROTEOMICS; TANDEM; PROTEINS;

D O I：

10.1002/pmic.201200439

中图分类号：

Q5 [生物化学];

学科分类号：

070307 [化学生物学];

摘要：

Proteomics research routinely involves identifying peptides and proteins via MS/MS sequence database search. Thus the database search engine is an integral tool in many proteomics research groups. Here, we introduce the Comet search engine to the existing landscape of commercial and open-source database search tools. Comet is open source, freely available, and based on one of the original sequence database search tools that has been widely used for many years.

引用

页码：22 / 24

页数：3

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