Role of adrenal stress hormones in forming lasting memories in the brain

被引:622
作者
McGaugh, JL [1 ]
Roozendaal, B
机构
[1] Univ Calif Irvine, Ctr Neurobiol Learning & Memory, Irvine, CA 92697 USA
[2] Univ Calif Irvine, Dept Neurobiol & Behav, Irvine, CA 92697 USA
关键词
D O I
10.1016/S0959-4388(02)00306-9
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Recent experiments investigating the effects of adrenal stress hormones on memory provide extensive evidence that epinephrine and glucocorticoids modulate long-term memory consolidation in animals and human subjects. Release of norepinephrine and activation of beta-adrenoceptors within the basolateral amygdala is critical in mediating adrenal stress hormone regulation of memory consolidation.
引用
收藏
页码:205 / 210
页数:6
相关论文
共 76 条
[71]   Blockade of isoproterenol-induced synaptic potentiation by tetra-9-aminoacridine in the rat amygdala [J].
Wang, SJ ;
Huang, CC ;
Hsu, KS ;
Tsai, JJ ;
Huang, CC ;
Gean, PW .
NEUROSCIENCE LETTERS, 1996, 214 (2-3) :87-90
[72]   Norepinephrine release in the amygdala after systemic injection of epinephrine or escapable footshock: Contribution of the nucleus of the solitary tract [J].
Williams, CL ;
Men, D ;
Clayton, EC ;
Gold, PE .
BEHAVIORAL NEUROSCIENCE, 1998, 112 (06) :1414-1422
[73]   The effects of noradrenergic activation of the nucleus tractus solitarius on memory and in potentiating norepinephrine release in the amygdala [J].
Williams, CL ;
Men, DS ;
Clayton, EC .
BEHAVIORAL NEUROSCIENCE, 2000, 114 (06) :1131-1144
[74]  
WILLIAMS CL, 1993, BEHAV NEUROSCI, V107, P1
[75]   The relationship between stress induced cortisol levels and memory differs between men and women [J].
Wolf, OT ;
Schommer, NC ;
Hellhammer, DH ;
McEwen, BS ;
Kirschbaum, C .
PSYCHONEUROENDOCRINOLOGY, 2001, 26 (07) :711-720
[76]   Cortisol differentially affects memory in young and elderly men [J].
Wolf, OT ;
Convit, A ;
McHugh, PF ;
Kandil, E ;
Thorn, EL ;
De Santi, S ;
McEwen, BS ;
de Leon, MJ .
BEHAVIORAL NEUROSCIENCE, 2001, 115 (05) :1002-1011