Droplet-based DNA purification in a magnetic lab-on-a-chip

被引：178

作者：

Lehmann, Ulrike ^{[1
]}

Vandevyver, Caroline

Parashar, Virendra K.

Gijs, Martin A. M.

机构：

[1] Ecole Polytech Fed Lausanne, Inst Microelect & Microsyst, CH-1015 Lausanne, Switzerland

[2] Ecole Polytech Fed Lausanne, Lab Chem Biotechnol, CH-1015 Lausanne, Switzerland

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 19期

关键词：

DNA; fluorescence; magnetic particles; microfluidics;

D O I：

10.1002/anie.200503624

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) Merge, mix, split, and transport are the main manipulation steps used for on-chip droplet-based DNA purification (see figure). The system is able to extract genomic material from dilute raw cell samples by using the actuation of magnetic microparticles within the droplets through a matrix of coils. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：3062 / 3067

页数：6

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