Aromin-A, an Annonaceous acetogenin from Annona cherimola

被引：29

作者：

Chen, CY ^{[1
]}

Chang, FR ^{[1
]}

Chiu, HF ^{[1
]}

Wu, MJ ^{[1
]}

Wu, YC ^{[1
]}

机构：

[1] Kaohsiung Med Coll, Grad Inst Nat Prod, Kaohsiung 807, Taiwan

来源：

PHYTOCHEMISTRY | 1999年 / 51卷 / 03期

关键词：

Annona cherimola; Annonaceae; aromin-A; squamocin;

D O I：

10.1016/S0031-9422(99)00002-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Chromatographic fractionation of a MeOH extract from the stems of Annona cherimola led to the isolation of a new nonadjacent, bis-THF ring acetogenin (one THF ring being at C-4 and the other at C-16), aromin-A (I) along with the known cytotoxic acetogenin squamocin (2). The structures of these isolates were established by means of mass spectrometry and spectroscopic techniques. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：429 / 433

页数：5

共 23 条

[1] Aromin and aromicin, two new bioactive annonaceous acetogenins, possessing an unusual bis-THF ring structure, from Xylopia aromatica (Annonaceae) [J].

Alfonso, D ;

ColmanSaizarbitoria, T ;

Zhao, GX ;

Shi, G ;

Ye, Q ;

Schwedler, JT ;

McLaughlin, JL .

TETRAHEDRON, 1996, 52 (12) :4215-4224

[2] THE RELATIVE CONFIGURATION OF ACETOGENINS ISOLATED FROM ANNONA-SQUAMOSA - ANNONIN-I (SQUAMOCIN) AND ANNONIN-VI [J].

BORN, L ;

LIEB, F ;

LORENTZEN, JP ;

MOESCHLER, H ;

NONFON, M ;

SOLLNER, R ;

WENDISCH, D .

PLANTA MEDICA, 1990, 56 (03) :312-316

[3] Acetogenins from seeds of Annona reticulata [J].

Chang, FR ;

Chen, JL ;

Chiu, HF ;

Wu, MJ ;

Wu, YC .

PHYTOCHEMISTRY, 1998, 47 (06) :1057-1061

[4] STUDIES ON THE ACETOGENINS OF FORMOSAN ANNONACEOUS PLANTS .2. CYTOTOXIC ACETOGENINS FROM ANNONA-RETICULATA [J].

CHANG, FR ;

WU, YC ;

DUH, CY .

JOURNAL OF NATURAL PRODUCTS, 1993, 56 (10) :1688-1694

[5]

CHANG FR, 1999, IN PRESS PHYTOCHEMIS

[6] Epomusenins A and B, two acetogenins from fruits of Rollinia mucosa [J].

Chen, YY ;

Chang, FR ;

Yen, HF ;

Wu, YC .

PHYTOCHEMISTRY, 1996, 42 (04) :1081-1083

[7] INHIBITION OF THE REPLICATION OF HEPATITIS-B VIRUS INVITRO BY 2',3'-DIDEOXY-3'-THIACYTIDINE AND RELATED ANALOGS [J].

DOONG, SL ;

TSAI, CH ;

SCHINAZI, RF ;

LIOTTA, DC ;

CHENG, YC .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (19) :8495-8499

[8] COMPARISON OF THE NEUTRAL RED AND METHYLENE-BLUE ASSAYS TO STUDY CELL-GROWTH IN CULTURE [J].

ELLIOTT, WM ;

AUERSPERG, N .

BIOTECHNIC & HISTOCHEMISTRY, 1993, 68 (01) :29-35

[9]

FUJIMOTO Y, 1994, CHEM PHARM BULL, V42, P1175, DOI 10.1248/cpb.42.1175

[10]

GU ZM, 1993, HETEROCYCLES, V36, P2221

← 1 2 3 →