Directed ortho metallation of deep cavity cavitands:: Functionalizing molecular concavity

被引：13

作者：

Laughrey, ZR ^{[1
]}

Gibb, BC ^{[1
]}

机构：

[1] Univ New Orleans, Dept Chem, New Orleans, LA 70148 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2006年 / 71卷 / 04期

关键词：

D O I：

10.1021/jo0513515

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Directed ortho metallation (DOM) processes have been used to functionalize the cavity and rim of title cavitand 1. The preorganization of the host resulted in a considerable reduction in the range of products produced. Thus, whereas sixty-nine products are possible from per-functionalization, only twelve were observed when the host was treated with three different alkyllithiums.

引用

页码：1289 / 1294

页数：6

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