Fluorescence "Switch on" of Conjugates of CdTe@ZnS Quantum Dots with Al, Ni and Zn Tetraamino-Phthalocyanines by Hydrogen Peroxide: Characterization and Applications as Luminescent Nanosensors

被引：36

作者：

Adegoke, Oluwasesan ^{[1
]}

Khene, Samson ^{[1
]}

Nyokong, Tebello ^{[1
]}

机构：

[1] Rhodes Univ, Dept Chem, ZA-6140 Grahamstown, South Africa

来源：

JOURNAL OF FLUORESCENCE | 2013年 / 23卷 / 05期

基金：

新加坡国家研究基金会;

关键词：

Quantum dots; Phthalocyanine; Hydrogen peroxide; Resonance energy transfer; AMINO ALUMINUM PHTHALOCYANINE; RED-REGION SUBSTRATE; ENERGY-TRANSFER; FLUOROMETRIC-DETERMINATION; OPTICAL-PROPERTIES; CAPPED CDTE; PHOTOLUMINESCENCE; BIOSENSOR; BEHAVIOR; SENSORS;

D O I：

10.1007/s10895-013-1222-x

中图分类号：

Q5 [生物化学];

学科分类号：

070307 [化学生物学];

摘要：

In this study, we have developed a novel nanoprobe for H2O2 based on the conjugation of CdTe@ZnS quantum dots (QDs) to different metal tetraamino-phthalocyanine (MTAPc): (M = (OAc)Al, {OAc = acetate}, Ni and Zn). Chemical coordination of the QDs to the MTAPc resulted in the fluorescence "switch off" of the linked QDs which was associated with Forster resonance energy transfer (FRET). In the presence of varying concentration of H2O2, the fluorescence of the linked QDs was progressively "switched on" and the FRET mechanism between the QDs and the MTAPc was disrupted. The sensitivity/limit of detection of the nanoprobe followed the order: QDs-ZnTAPc (2.2 mu M) > QDs-NiTAPc (4.4 mu M) > QDs-AlTAPc (9.8 mu M) while the selectivity followed the order: QDs-NiTAPc > QDs-AlTAPc > QDs-ZnTAPc. The varying degree of sensitivity/selectivity and mechanism of detection is discussed in detail.

引用

页码：963 / 974

页数：12

共 54 条

[1]

SYNTHESIS AND STRUCTURAL STUDIES OF METAL(II) 4,9,16,23-PHTHALOCYANINE TETRAAMINES [J].