The intramolecular alkylation of arenes by higher cyclic ethers provides a stereoefficient route to tetralins

被引：6

作者：

Harrowven, DC

Dainty, RF

机构：

[1] Department of Chemistry, The University, Southampton

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 40期

关键词：

D O I：

10.1016/S0040-4039(97)01636-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Tetrahydrofurans and tetrahydropyrans tethered to arenes through a propyl chain readily undergo cyclisation to tetralins when exposed to titanium tetrachloride. The reaction has been shown to be highly stereospecific and an S(N)2 type mechanism is implicated. (C) 1997 Elsevier Science Ltd.

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页码：7123 / 7124

页数：2

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