Nitric oxide: an antiparasitic molecule of invertebrates

被引：161

作者：

Rivero, A ^{[1
]}

机构：

[1] CSIC, Museo Nacl Ciencias Nat, Dept Evolutionary Ecol, E-28006 Madrid, Spain

来源：

TRENDS IN PARASITOLOGY | 2006年 / 22卷 / 05期

关键词：

D O I：

10.1016/j.pt.2006.02.014

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Since Furchgott, Ignarro and Murad won the Nobel prize in 1998 for their work on the role of nitric oxide (NO) as a signaling molecule, many reports have shown the seemingly limitless range of body functions controlled by this compound. In vertebrates, the role of NO as a defense against infection caused by viruses, bacteria, and protozoan and metazoan parasites has been known for several years. New evidence, however, shows that NO is also important in defending invertebrates against parasites. This discovery is a breakthrough in the understanding of how the invertebrate immune system works, and it has implications for the emerging field of invertebrate ecological immunology.

引用

页码：219 / 225

页数：7

共 70 条

[31] INTERSPECIFIC COMPETITION BETWEEN STEINERNEMATID NEMATODES WITHIN AN INSECT HOST [J].

KOPPENHOFER, AM ;

KAYA, HK ;

SHANMUGAM, S ;

WOOD, GL .

JOURNAL OF INVERTEBRATE PATHOLOGY, 1995, 66 (02) :99-103

[32] Trade-off between parasitoid resistance and larval competitive ability in Drosophila melanogaster [J].

Kraaijeveld, AR ;

Godfray, HCJ .

NATURE, 1997, 389 (6648) :278-280

[33] Protection of mice previously infected with Plasmodium vinckei against subsequent Salmonella enteritidis infection is associated with nitric oxide production capacity [J].

Kremsner P.G. .

Parasitology Research, 1997, 84 (1) :63-68

[34] Mosquito -: Plasmodium interactions in response to immune activation of the vector [J].

Lowenberger, CA ;

Kamal, S ;

Chiles, J ;

Paskewitz, S ;

Bulet, P ;

Hoffmann, JA ;

Christensen, BM .

EXPERIMENTAL PARASITOLOGY, 1999, 91 (01) :59-69

[35] Aedes aegypti: Induced antibacterial proteins reduce the establishment and development of Brugia malayi [J].

Lowenberger, CA ;

Ferdig, MT ;

Bulet, P ;

Khalili, S ;

Hoffmann, JA ;

Christensen, BM .

EXPERIMENTAL PARASITOLOGY, 1996, 83 (02) :191-201

[36] The mosquito Anopheles stephensi limits malaria parasite development with inducible synthesis of nitric oxide [J].

Luckhart, S ;

Vodovotz, Y ;

Cui, LW ;

Rosenberg, R .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (10) :5700-5705

[37] Gene structure and polymorphism. Of an invertebrate nitric oxide synthase gene [J].

Luckhart, S ;

Rosenberg, R .

GENE, 1999, 232 (01) :25-34

[38] Anopheles gambiae immune gene variants associated with natural Plasmodium infection [J].

Luckhart, S ;

Li, KY ;

Dunton, R ;

Lewis, EE ;

Crampton, AL ;

Ryan, JR ;

Rosenberg, R .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 2003, 128 (01) :83-86

[39] Nitric oxide and macrophage function [J].

MacMicking, J ;

Xie, QW ;

Nathan, C .

ANNUAL REVIEW OF IMMUNOLOGY, 1997, 15 :323-350

[40] Within-host interactions of Lymantria dispar (Lepidoptera: Lymantriidae) nucleopolyhedrosis virus and Entomophaga maimaiga (Zygomycetes: Entomophthorales) [J].

Malakar, R ;

Elkinton, JS ;

Hajek, AE ;

Burand, JP .

JOURNAL OF INVERTEBRATE PATHOLOGY, 1999, 73 (01) :91-100

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