Cord Blood 25-Hydroxyvitamin D Levels and the Risk of Acute Lower Respiratory Tract Infection in Early Childhood

被引：38

作者：

Mohamed, W. A. Wahab ^{[1
,2
]}

Al-Shehri, M. A. ^{[3
]}

机构：

[1] Menia Univ, Fac Med, Dept Pediat, Al Minya, Egypt

[2] King Khalid Univ, Coll Med, Dept Pediat, Abha, Saudi Arabia

[3] Abha Gen Hosp, Dept Biochem, Abha, Saudi Arabia

来源：

JOURNAL OF TROPICAL PEDIATRICS | 2013年 / 59卷 / 01期

关键词：

cord blood; 25-hydroxyvitamin D; acute lower respiratory tract infection; early childhood; VITAMIN-D STATUS; HIGH PREVALENCE; PREGNANT-WOMEN; D DEFICIENCY; BRONCHIOLITIS; SEVERITY; NEWBORNS; ASTHMA;

D O I：

10.1093/tropej/fms042

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Objective: To determine the relationship between cord blood 25-hydroxyvitamin D [25 (OH) D] concentrations and the subsequent risk of acute lower respiratory tract infection (ALRI) in the first 2 years of life. Patients and Methods: Cord blood from 206 newborns was tested for 25 (OH) D. Medical records covering the first 2 years of life were reviewed, and the diagnosis of ALRI was recorded. Results: Sixty-two (30.1%) infants developed ALRI in their first 2 years of life, of whom 49 (79%) infants had bronchiolitis and 13 (21%) infants had pneumonia. Concentrations of 25 (OH) D were lower in infants who developed ALRI compared with those did not (p < 0.0001). Vitamin D deficiency was associated with increased risk of ALRI (p = 0.000). Conclusion: Low cord blood 25 (OH) D levels are associated with increased risk of ALRI in the first 2 years of life.

引用

页码：29 / 35

页数：7

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