Antioxidant polyketide phenolic metabolites from the edible mushroom Cortinarius purpurascens

被引：47

作者：

Bai, Ming-Sheng ^{[1
,2
]}

Wang, Chen ^{[1
]}

Zong, Shi-Chun ^{[3
]}

Lei, Ming ^{[1
]}

Gao, Jin-Ming ^{[1
]}

机构：

[1] Northwest A&F Univ, Coll Sci, Shaanxi Engn Ctr Bioresource Chem & Sustainable U, Yangling 712100, Shaanxi, Peoples R China

[2] Ningxia Univ, Coll Life Sci, Ningxia, Peoples R China

[3] Xian Univ Posts & Telecommun, Div Med Clin, Xian 710061, Shaanxi, Peoples R China

来源：

FOOD CHEMISTRY | 2013年 / 141卷 / 04期

基金：

中国国家自然科学基金;

关键词：

Cortinarius purpurascens; Antioxidant activity; Anthraquinones; Polyketides; Fungal pigments; EXTRACTS; ASSAY;

D O I：

10.1016/j.foodchem.2013.05.099

中图分类号：

O69 [应用化学];

学科分类号：

070301 [无机化学];

摘要：

Phytochemical investigation of the ethyl acetate extract of the edible macrofungus, Cortinarius purpurascens, led to the isolation of nine anthraquinone-related pigments, citreorosein 6,8-dimethyl ether (1), physcione (2), rufoolivacin (3), rufoolivacin C (4), rufoolivacin D (5), leucorufoolivacin (6), verbindung cr11 (7), verbindung cr60 (8) and 1-Hydroxy-3-methyl-2-isopropanyl-6,8-dimethoxyanthraquinone (9). The structures of these isolated compounds were characterised by spectroscopic methods and comparison with published data. Among the tested compounds, 3-6 exhibited potent DPPH radical-scavenging activity with IC50 values in the range of 3-8 mu g/ml. The results indicated that the fungus is a possible source of natural products with potential antioxidant activity. (C) 2013 Elsevier Ltd. All rights reserved.

引用

页码：3424 / 3427

页数：4

共 25 条

[1]

Hispidin produced from Phellinus linteus protects against peroxynitrite-mediated DNA damage and hydroxyl radical generation [J].