Molecular iodine in isopropenyl acetate (IPA): a highly efficient catalyst for the acetylation of alcohols, amines and phenols under solvent free conditions

被引：62

作者：

Ahmed, Naseem ^{[1
]}

van Lier, Johan E. ^{[1
]}

机构：

[1] Univ Sherbrooke, Fac Med, Dept Med Nucl & Radiobiol, Sherbrooke, PQ J1H 5N4, Canada

来源：

TETRAHEDRON LETTERS | 2006年 / 47卷 / 30期

基金：

加拿大健康研究院;

关键词：

iodine; Lewis acid; isopropenyl acetate (IPA); acetylation; alcohols; amines;

D O I：

10.1016/j.tetlet.2006.05.122

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Iodine in isopropenyl acetate (IPA) is a highly efficient catalyst for the acetylation of a variety of alcohols, phenols and amines under solvent free conditions. Primary, secondary, tertiary alcohols, amines and mono to polybydroxy phenols and anilines with electron donating or withdrawing substituents can be easily acetylated in good to excellent yield at 85-90 degrees C. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：5345 / 5349

页数：5

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