Prader-Willi syndrome

被引：16

作者：

Couper, RTL ^{[1
]}

机构：

[1] Univ Adelaide, Womens & Childrens Hosp, Dept Paediat, N Adelaide, SA 5006, Australia

来源：

JOURNAL OF PAEDIATRICS AND CHILD HEALTH | 1999年 / 35卷 / 04期

关键词：

behavioural problems; genetics; Prader-Willi syndrome;

D O I：

10.1046/j.1440-1754.1999.00397.x

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Prader-Willi syndrome is a multi system disorder characterized by neonatal hypotonia, later obesity, hyperphagia and mental retardation. It occurs sporadically, either as a result of microdeletion of chromosome 15p (70%) or as a result of maternal disomy of chromosome 15 (30%). The major problems encountered by parents are those of hyperphagia, food-seeking and obesity, and conduct disorder, particularly tantrums or oppositional behaviour.

引用

页码：331 / 334

页数：4

共 43 条

[1]

ABEHHAIM L, 1996, NEW ENGL J MED, V335, P609

[2]

Akefeldt A, 1995, DEV MED CHILD NEUROL, V37, P1101

[3]

Bhargava SA, 1996, PEDIATRICS, V97, P265

[4]

BUTLER MG, 1991, PEDIATRICS, V88, P853

[5]

Cassidy SB, 1997, AM J MED GENET, V68, P433

[6]

CASSIDY SB, 1989, AM J HUM GENET, V44, P806

[7]

CURFS LMG, 1991, CLIN GENET, V40, P430

[8] THE USE OF FLUOXETINE IN AN ADOLESCENT WITH PRADER-WILLI SYNDROME [J].

DECH, B ;

BUDOW, L .

JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, 1991, 30 (02) :298-302

[9] THE PRADER-WILLI-SYNDROME [J].

DONALDSON, MDC ;

CHU, CE ;

COOKE, A ;

WILSON, A ;

GREENE, SA ;

STEPHENSON, JBP .

ARCHIVES OF DISEASE IN CHILDHOOD, 1994, 70 (01) :58-63

[10]

DOWN JL, 1887, MENTAL AFFECTIONS CH, P100

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