Prader-Willi syndrome

被引：16

作者：

Couper, RTL ^{[1
]}

机构：

[1] Univ Adelaide, Womens & Childrens Hosp, Dept Paediat, N Adelaide, SA 5006, Australia

来源：

JOURNAL OF PAEDIATRICS AND CHILD HEALTH | 1999年 / 35卷 / 04期

关键词：

behavioural problems; genetics; Prader-Willi syndrome;

D O I：

10.1046/j.1440-1754.1999.00397.x

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Prader-Willi syndrome is a multi system disorder characterized by neonatal hypotonia, later obesity, hyperphagia and mental retardation. It occurs sporadically, either as a result of microdeletion of chromosome 15p (70%) or as a result of maternal disomy of chromosome 15 (30%). The major problems encountered by parents are those of hyperphagia, food-seeking and obesity, and conduct disorder, particularly tantrums or oppositional behaviour.

引用

页码：331 / 334

页数：4